{"id":1189,"date":"2021-11-06T21:06:31","date_gmt":"2021-11-07T02:06:31","guid":{"rendered":"https:\/\/sites.imsa.edu\/hadron\/?p=1189"},"modified":"2021-11-06T21:07:14","modified_gmt":"2021-11-07T02:07:14","slug":"new-covid-19-variant-spreading-across-south-america-and-the-united-states","status":"publish","type":"post","link":"https:\/\/sites.imsa.edu\/hadron\/2021\/11\/06\/new-covid-19-variant-spreading-across-south-america-and-the-united-states\/","title":{"rendered":"New COVID-19 Variant Spreading Across South America and the United States"},"content":{"rendered":"<p style=\"text-align: center\"><span style=\"font-weight: 400\">Written by: Samuel Go<\/span><\/p>\n<p><span style=\"font-weight: 400\">A COVID-19 variant from Colombia called Mu has spread across the entire US, leading the World Health Organization to declare it a variant of interest. A team of Japanese researchers published an unreviewed preprint paper on September 7 detailing how the Mu variant was more resistant to vaccines than all other COVID-19 strains, including Delta. However, Delta remains much more competitive and dangerous than any other COVID-19 variant, including Mu.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>How is this variant different from Delta?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Mu was first sequenced in Colombia in January 2021 and declared a variant of interest on August 30, 2021, by the World Health Organization. It is still a new variant, so there is not much known about the differences between it and widespread COVID-19 strains like Delta. A group of Japanese researchers did discover that Mu was more resistant to vaccines than any other strain of COVID-19, including Delta. However, the research paper has still not been peer-reviewed as of September 11, 2021, so the findings are not conclusive. There is still not much information about Mu as there have been so few studies on the variant.<\/span><\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">Figure 1<\/span><\/p>\n<p style=\"text-align: center\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1193\" src=\"http:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image1-300x135.png\" alt=\"\" width=\"300\" height=\"135\" srcset=\"https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image1-300x135.png 300w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image1-122x55.png 122w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image1-400x180.png 400w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image1.png 512w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1195\" src=\"http:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image2-300x141.png\" alt=\"\" width=\"300\" height=\"141\" srcset=\"https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image2-300x141.png 300w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image2-117x55.png 117w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image2-400x188.png 400w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image2.png 512w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1194\" src=\"http:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image3-300x139.png\" alt=\"\" width=\"300\" height=\"139\" srcset=\"https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image3-300x139.png 300w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image3-118x55.png 118w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image3-400x186.png 400w, https:\/\/sites.imsa.edu\/hadron\/files\/2021\/11\/HadronNovember2021Figure1Image3.png 512w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">(A) Daily new Colombian COVID-19 cases on the y-axis. Date on the x-axis. Percentage of cases caused by a particular strain as colored bars.<\/span><\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">(B) Virus neutralization assay comparing the geometric mean titers of previously infected people. A lower number on top of the bars means that a virus can only be detected under a more concentrated blood serum sample and vice versa. A lower number on top also means that the virus can better evade antibodies targeting it compared to other viruses.<\/span><\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">(C) Same as (B) but with vaccinated people<\/span><\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">Source: <\/span><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.09.06.459005v1.full\"><i><span style=\"font-weight: 400\">BioRxiv<\/span><\/i><\/a><i><span style=\"font-weight: 400\">\u00a0<\/span><\/i><\/p>\n<p>&nbsp;<\/p>\n<p><b>How concerned should we be about Mu?<\/b><\/p>\n<p><span style=\"font-weight: 400\">From the information available, Mu may be more genetically resistant to COVID-19 immunity from vaccines and infection than other strains. As a result, it may cause breakthrough infections for those who have already been infected by other COVID-19 strains. However, vaccines still protect against serious cases of COVID-19 from even the most genetically resistant strains like Beta and potentially Mu.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Over the summer, the percentage of total active Colombian COVID-19 cases caused by Mu fell by 6 percent while the percentage of Delta cases rose by 13 percent. The data indicates that Mu is nowhere near Delta in terms of infectiousness. Even though Mu is more resistant to treatment, it is nowhere near as concerning as Delta, which is much more transmissible than Mu and therefore able to outcompete it anywhere.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Conclusion<\/b><\/p>\n<p><span style=\"font-weight: 400\">Currently, nobody knows whether Mu will become the new \u201csuper-variant.\u201d Mu may be worse than Delta because it is more resistant to vaccination and treatment, but Delta has already outcompeted Mu everywhere, even in Colombia where Mu originated. The best course of action to stop COVID-19, according to many health experts, is to focus completely on containing the spread of Delta through public health efforts like vaccination campaigns, enforcing social distancing, and mask mandates.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">References and Sources<\/span><\/p>\n<p><span style=\"font-weight: 400\">Cheng, M. (2021, September 8). What is the mu variant of the coronavirus?. Retrieved September 11, from <\/span><a href=\"https:\/\/apnews.com\/article\/lifestyle-health-europe-united-states-coronavirus-pandemic-9bc7b53dc5c119ddcfe7e124ae329ed4\"><span style=\"font-weight: 400\">https:\/\/apnews.com\/article\/lifestyle-health-europe-united-states-coronavirus-pandemic-9bc7b53dc5c119ddcfe7e124ae329ed4<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Lovelace Jr., B. (2021, September 7). WHO says delta remains the \u2018most concerning\u2019 Covid variant despite emergence of mu. Retrieved September 11, 2021, from <\/span><a href=\"https:\/\/www.cnbc.com\/2021\/09\/07\/mu-covid-variant-who-says-delta-remains-most-concerning.html\"><span style=\"font-weight: 400\">https:\/\/www.cnbc.com\/2021\/09\/07\/mu-covid-variant-who-says-delta-remains-most-concerning.html<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">McNamara, D. (2021, September 9). Q&amp;A: How Concerned Should We Be About the Mu Variant?. Retrieved September 15, from <\/span><a href=\"https:\/\/www.webmd.com\/lung\/news\/20210909\/mu-covid-variant-qa\"><span style=\"font-weight: 400\">https:\/\/www.webmd.com\/lung\/news\/20210909\/mu-covid-variant-qa<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tracking SARS-CoV-2 variants. (2021, September 2). Retrieved September 11, 2021, from\u00a0 <\/span><a href=\"https:\/\/www.who.int\/en\/activities\/tracking-SARS-CoV-2-variants\/\"><span style=\"font-weight: 400\">https:\/\/www.who.int\/en\/activities\/tracking-SARS-CoV-2-variants\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Wadman, M. (2021, September 7). United States boosts tracking of coronavirus strains as Mu variant draws scrutiny. Retrieved September 11, 2021, from <\/span><a href=\"https:\/\/www.science.org\/content\/article\/united-states-boosts-tracking-coronavirus-strains-mu-variant-draws-scrutiny\"><span style=\"font-weight: 400\">https:\/\/www.science.org\/content\/article\/united-states-boosts-tracking-coronavirus-strains-mu-variant-draws-scrutiny<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400\">Williams, K. et al. (n.d.). Antibody Titers, Retrieved September 15, from <\/span><a href=\"https:\/\/vcahospitals.com\/know-your-pet\/antibody-titres\"><span style=\"font-weight: 400\">https:\/\/vcahospitals.com\/know-your-pet\/antibody-titres<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Written by: Samuel Go A COVID-19 variant from Colombia called Mu has spread across the entire US, leading the World Health Organization to declare it a variant of interest. A team of Japanese researchers published an unreviewed preprint paper on September 7 detailing how the<\/p>\n","protected":false},"author":707,"featured_media":1202,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-1189","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/posts\/1189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/comments?post=1189"}],"version-history":[{"count":2,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/posts\/1189\/revisions"}],"predecessor-version":[{"id":1204,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/posts\/1189\/revisions\/1204"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/media\/1202"}],"wp:attachment":[{"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/media?parent=1189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/categories?post=1189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.imsa.edu\/hadron\/wp-json\/wp\/v2\/tags?post=1189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}